Brazil raised its score to 18 points, compared to 12 for Argentina and 9 for Ecuador in the unified group that includes ten teams, and four qualify directly for the next World Cup.
Neymar scored the first goal for Brazil in the fourth minute from close range, after a cross from Gabriel Jesus.
Neymar also played a crucial pass for Lucas Paqueta, who scored the second goal, with a smart ground shot in the last moments (90 + 3).
Paraguay, which fell to sixth place in the standings, sought to seize a late goal that denied Brazil a return to victory, but the last word was for Paqueta, who scored the goal of reassurance in the last breath.
Although the match was held behind closed doors, coach Titi’s men managed to achieve the victory over Paraguay in their own home.
The match between Colombia and Argentina ended in a 2-2 draw at dawn on Wednesday in the South American qualifiers for the FIFA World Cup Qatar 2022™.
Argentina benefited from three draws in Tuesday’s five matches, to stay 3 points behind Ecuador, the third.
Argentina is ranked second with 12 points, while Colombia is in fifth place with 8 points.